RECOVERIX PRO

NEUROTECHNOLOGY

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COMPLETE NEUROREHABILITATION SOLUTION

recoveriX Neurotechnology is a BCI-based closed-loop stroke rehabilitation system to train upper or lower extremities of patients who suffer from motor impairments due to stroke. It is ready to be used in your hospital or rehabilitation center to treat stroke patients.

recoveriX is the first brain-computer interface rehabilitation system that pairs mental activities (specifically, the imagination of movement) with visual and tactile feedback in real-time. If a subject imagines a joint movement and receives visual feedback through a virtual avatar, and tactile feedback through electrical muscle stimulation at the same time, then this rewarding feedback encourages the patient to imagine the movement correctly.

Beyond facilitating patient compliance, the simultaneous activation of both sensory and motor functions is essential in brain plasticity. That is, if the brain areas that control movements are active at the same time that feedback is provided, the brain areas should recover more effectively. On the other hand, if the patient receives feedback while not imagining hand movement, recovery will be poor.

PRODUCT HIGHLIGHTS

Hand therapy mode
Foot therapy mode (research mode)
Classification accuracy to quantify patient's performance
Easy, online EEG quality control
Real-time event-related desynchronization maps
Real-time functional stimulation of hands and legs
Mirror neuron system activation with a virtual avatar
Easy to understand instructions for the patient
Fully guided therapy runs for 45 minutes
CE certified medical product

TECHNICAL SPECIFICATIONS

Active EEG electrodes for perfect data quality16
Wireless EEG headset resolution 24 Bit
Functional electrical stimulator current1-60 mA
Battery life EEG headset>8 hours

3 IN 1 - A UNIQUE COMBINATION

A neurological disorder might inhibit the ability to move hands, arms or feet, but maybe not the ability to imagine the movement! Patients are instructed to imagine a hand or a foot movement. Once the recoveriX system has recognized the motor imagery successfully, virtual reality and functional electrical stimulation will be activated.

With three different kinds of neurofeedback, recoveriX improves brain plasticity and thus, the therapy success.

  • MOTOR IMAGERY (MI)
    Imagine a hand or a foot movement. recoveriX measures and analyses brain waves, which reflect the motor imagery and determines whether the motor imagery was correct. Once motor imagery has been recognized, virtual reality and functional electrical stimulation will be activated.
  • VIRTUAL REALITY (VR)
    The simulation on the screen makes motor imagery visible. Patients sit in front of a screen, where they see hands and feet of an avatar. This gives patients the feeling of watching their own movements in front of a mirror. If recoveriX recognizes motor imagery of the movement (such as a right hand movement), the avatar moves the right hand.
  • FUNCTIONAL ELECTRICAL STIMULATION (FES)
    For this stimulation, two electrodes are placed (for example) on the dorsiflexors of the wrist or on the leg. If the system recognizes a correct motor imagery, the muscles get electrically stimulated, causing a real movement. This should help you re-learn how to initiate movement, and thus make movement possible again.

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SYSTEM COMPONENTS

recoveriX PRO Neurotechnology comes with a personal computer that controls the components and accessories of the device. The external monitor is placed in front of the patient. The visual feedback shows the patient’s hands in a first-person perspective or feet in a mirror perspective. Two Functional Electrical Stimulators are stimulating the muscles, performing the dorsiflexion of both joints.

Finally, an EEG cap with 16 channels is included and allows a wireless charging and a fast switch from one patient’s cap to the other.

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MONITORING PATIENTS' PARTICIPATION

Patients may may misunderstand the instructions to imagine (or try to perform) specific movements while receiving feedback. Patients may be tired, depressed (including post-stroke depression), distracted, or perform compensatory strategies such as imagining the shoulder. If the patient does not imagine the movement, therapy will be less effective, leading to poorer outcomes.

recoveriX PRO gives an real-time feedback showing if the patient is doing every motor imagination correctly. This usually leads to a much higher level of motivation.

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ADD RECOVERIX IN YOUR PRIVATE REHAB PRACTICE

recoveriX can be added into your neurological rehabilitation practice which gives you a competitive advantage. Think about the statistical number of stroke patients in your region and you’ll get a rough idea of how many potential patients you can treat with recoveriX.

By servicing a complete region, you create a unique selling proposition because there is no treatment comparable to recoveriX. The more recoveriX systems you have, the more patients you can treat simultaneously.

FRANCHISE OPPORTUNITY

ADD RECOVERIX TO YOUR HOSPITAL OR REHABILITATION CENTER

When patients suffer a stroke or other neurological injury, they are hospitalized. In this acute phase, rehabilitation is most relevant and determine success of the mostly long-lasting recovery process. recoveriX is easy to use and mobile and can be used already with hospitalized patients at bedside.

Afterwards, recoveriX can be used in the rehabilitation center in the sub-acute phase.  recoveriX trains the brain and therefore supplements standard physical therapy in the subacute phase.

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NEURO REHABILITATION WITH BRAIN-COMPUTER INTERFACE TECHNOLOGY

recoveriX is an innovative and unique neurotechnology for the rehabilitation of patients with neurological disorders caused by stroke or brain injury. It helps the patient regain functions of the upper and lower extremities.

recoveriX supplements standard physical therapy with the chance for a quicker and more successful recovery. Also, when standard therapy can no longer yield any further benefit, recoveriX provides a second chance for improvements. It can be used in the acute, sub-acute, or chronic states.

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THE POSITIVE IMPACT

There are multiple positive impacts of recoveriX therapy ranging from decreases in pain, spasticity, tremor, improvements of motor movements, passive joint movements, sensitivity and, interestingly enough, in gait. Patients also report that upper and lower limbs feel warmer and sometimes, even memory, concentration and speech functions improve. All these positive effects can be explained by the activation of both hemispheres by the recoveriX therapy.

recoveriX is highly effective even 10, 20 or 30 years after the brain injury, stroke…

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STUDIES HAVE SHOWN THAT...

  • 99% of patients improve spasticity
  • 99% of patients improve daily activities
  • 99% of patients improve their gross motor functions
  • 99% of patients improve their mental performance
  • 95% of patients improve their fine motor skills
  • 95% of patients improve their concentration
  • 0% side effects

MORE RESULTS FROM THE STUDY…

The clinical effectiveness was shown in a group study with 52 patients who improved in motor functions and spasticity highly significant.

The recoveriX PRO study investigated 52 patients (3.3 years after stroke) with a mean FMA-UE (Fugl-Meyer Assessment of Upper Extremities) at baseline of 17.0 points. The study showed a signifanct improvement of FMA-UE of 4.76*** points.

Severly impaired patients (FMA-UE: 0-28) improved 3.8*** points, moderatley impaired patients (FMA-UE: 29-42) improved 7.99*** points, mildly impaired patients (FMA-UE: 43-66) improved 5.29*** points. People that achieved an average classification accuracy >80 % improved by 6.5 points, people that were below 80 % had an improvement of 2.3 points.

 

The following tests showed additionally a significant improvement: Bartel**, Modified Ashworth Scale Wrist***, Modified Ashworth Scale Fingers***, Box and Block Test of Affected Hand**, Box and Block Test of Healthy Hand***, 9-hole PEG Test of Affected Hand*, 9-hole PEG Test of Healthy Hand***, Fahn Tremor Rating Scale of Affected Hand**, Fahn Tremor Rating Scale of Healthy Hand**, Lower Extremity Fugl Meyer Assessment*, Montreal Cognitive Assessment*, Stroop Color-Word Test**.

Other control studies got on average an improvement of 3.92 points in FMA-UE (FES, robotic movement, visual feedback). *** <0.001, ** <0.01

Stephen et al. (2012) defined the clinically important difference (CID) for moderately to minimally impaired patients in chronic stroke. This CID refers to the UE-FM improvement and is 4.25 to 7.25 points. recoveriX achieved for moderately impaired patients 7.99 points which is higher than the CID. For minimally impared patients, recoveriX achieved 5.29 points which is in the range of the CID. Furthermore, the study showed that recoveriX leads to the same improvement independent of how long ago the stroke happened (Range: 6 month to 31 years).

FREQUENTLY ASKED QUESTIONS

Is a disorder of cognition and/or attention an exclusion criteria?

A significant disorder in language, cognition, and/or attention (such as Wernicke’s aphasia or dementia), which prevents the patient from understanding the tasks and/or performing these tasks, is an exclusion criterion.

Is recoveriX therapy also appropriate for people with a history of epilepsy?

The recoveriX treatment can also be used for patients with epilepsy, but the final decision is done by your family doctor.

How much instruction do I need to successfully perform recoveriX therapy?

Patients do not need a separate therapy session for the instruction – they can start with the therapy immediately. The patients only need to learn the general procedure and simple instructions for the therapy session before the first session. The first session is already part of the therapy.

Which movements can be trained with recoveriX?

recoveriX provides functional muscle stimulation of the left and right arm to perform a dorsiflexion and of the left or right foot. This improves lower and upper limb functions.

Can recoveriX be combined with traditional physiotherapy or occupational therapy?

Yes. Actually, recoveriX combines 3 standard therapies into one treatment: (i) functional electrical stimulation, (ii) motor imagery and (iii) mirror neuron therapy. Additional physical therapy can be beneficial for the patient.

When is the most effective time to do recoveriX therapy?

recoveriX can be used for stroke rehabilitation across the acute, sub-acute, and chronic stages, as various patient cases have shown. Our scientific study has shown that recoverX therapy is effective even 10, 20, 30,… years after the stroke or neurological disorder occured.

How often should recoveriX therapy be done?

It is recommended to perform recoveriX therapy for a complete course of 25 therapy sessions, with 3 sessions per week, each lasting for about 1 hour. Of course, it is also possible to participate in other therapies or rehabilitation programs. We know that patients are likely to improve more, the more therapy he/she gets.

Are the improvements long-lasting?

Yes, the improvements are long-lasting and remain permanently.

How long does a recoveriX treatment take?

One recoveriX block contains 25 therapies. 3 therapy sessions per week are recommended. Patients can have up to 2 treatments per day. This is especially useful to reduce exhausting travel time.

For what patients is recoveriX therapy appropriate?

recoveriX is a rehabilitation system specifically developed for patients with neurological deficits. Patients who had a stroke, a traumatic brain injury or another brain injury can do the therpay. Furthermore, patients with hemiplegia, movement impairments resulting from brain damage, pain, spasticity or Multiple Sklerosis can benefit from the therapy.

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