HISYS
REAL-TIME BIOSIGNAL ACQUISITION, PROCESSING AND NEUROSCIENCE APPLICATION DEVELOPMENT
HIGH-SPEED REAL-TIME BIOSIGNAL PROCESSING FOR MATLAB & SIMULINK
Build, test and run real-time neuroscience applications from biosignal acquisition to BCI and closed-loop control.
g.HIsys is a real-time biosignal acquisition and processing platform for MATLAB and Simulink, designed for neuroscience, BCI development and closed-loop research. Acquire EEG, ECoG, ECG, EMG, EOG, fNIRS and other biosignals from g.tec amplifiers, process signals in real time, extract features, classify brain activity and control feedback or stimulation.
Use ready-to-run g.tec processing blocks and applications or develop custom algorithms and real-time pipelines with Simulink, MATLAB and C. With support for LSL, UDP and multimodal data integration, g.HIsys enables researchers and BCI developers to move from signal acquisition to real-time analysis, BCI control and closed-loop applications within one development environment.
To read more about neuroscience experiments with g.tec technology, please visit our Frontiers profile.
| Real-time biosignal acquisition for EEG, ECoG, ECG, EMG, EOG, fNIRS and other biosignals |
| Real-time signal processing directly in MATLAB/Simulink |
| MATLAB and Simulink integration for custom real-time biosignal applications |
| Custom algorithm development using standard Simulink blocks, MATLAB S-Functions or C S-Functions |
| Real-time feature extraction including bandpower, FFT, PSD, ERD, spectrograms, averages and Hjorth parameters |
| Online classification for real-time BCI and biosignal-driven applications |
| BCI development for P300, SSVEP/SSSEP, motor imagery and slow cortical potential paradigms |
| Closed-loop control linking biosignal activity to feedback, stimulation or external devices |
| OSCAR LIVE for real-time EEG artifact removal |
| Real-time EEG signal quality and impedance monitoring |
| Simultaneous acquisition from multiple g.tec amplifiers |
| Multimodal acquisition combining EEG with fNIRS, eye tracking and other physiological signals |
| High-speed data streaming and storage is optimized for high channel counts and sampling rates up to 38.4 kHz per channel |
| UDP and Lab Streaming Layer (LSL) interfaces for communication with external systems |
| Real-time visualization of raw signals, spectra, spectrograms and evoked potentials |
| 3D visualization and mapping of EEG/ECoG activity and signal-quality parameters |
| Experimental paradigm presentation with synchronized visual and auditory stimuli |
| Digital I/O for experimental triggers and external device control |
| Real-time control of g.Estim PRO and g.Estim FES stimulation systems |
| Integration of g.BSanalyze processing and classification results into real-time g.HIsys applications |
| Ready-to-run Simulink models and specialized processing blocks in g.HIsys Professional |
| Software environment | MATLAB / Simulink |
| Software versions | BASIC / PROFESSIONAL |
| Supported amplifiers | g.HIamp, g.Nautilus, g.USBamp, Unicorn BCI Core-8 |
| Real-time acquisition | Supported |
| Real-time signal processing | Supported |
| Maximum visualization channels | Up to 1,024 channel |
| Maximum data streaming rate | Up to 38.4 kHz per channel |
| Supported signal types | EEG, ECoG, ECG, EMG, EOG, fNIRS and other biosignals |
| Feature extraction | Bandpower, FFT, PSD, ERD, spectrogram, averages, Hjorth parameters and others |
| Online classification | Supported |
| Artifact removal | OSCAR LIVE real-time EEG artifact removal |
| Signal quality monitoring | EEG quality and impedance monitoring |
| Visualization | Raw signals, spectra, spectrograms, evoked potentials and 3D visualization |
| Brain mapping | 3D head and cortical visualization |
| External communication | UDP, Lab Streaming Layer (LSL) |
| Multimodal integration | fNIRS, eye tracking and other external data sources |
| Custom processing | MATLAB S-Functions, C S-Functions and Simulink blocks |
| Data access | MATLAB workspace and MATLAB-compatible data |
| Stimulation interfaces | g.Estim PRO, g.Estim FES and compatible g.tec interfaces |
| Developer interface | Simulink, MATLAB S-Functions and C S-Functions |
| Custom algorithms | MATLAB and C S-Function support |
| External system integration | UDP and LSL interfaces |
| Real-time application development | Custom acquisition, processing, classification, visualization and closed-loop workflows |
| Professional model library | 118 ready-to-run Simulink models |
| Professional processing library | 89 signal-processing blocks |
| Professional block libraries | 19 g.HIsys block libraries |
SYNCHRONIZED BIOSIGNALS AND EYE TRACKING
g.HIsys can acquire eye-tracking data together with EEG and other biosignals in the same real-time Simulink environment. Gaze coordinates can be visualized, processed and stored alongside biosignal data, enabling synchronized analysis of neural activity and visual behavior.
Supported eye-tracking workflows include Tobii Pro systems, with synchronization of gaze data, EEG and experimental events for cognitive neuroscience, visual attention and human-computer interaction studies.
CONNECT BIOSIGNALS TO EXTERNAL APPLICATIONS
The g.HIsys UDP interface allows real-time exchange of biosignals, extracted parameters, classification results and trigger information between Simulink and external applications. This enables g.HIsys to communicate with VR systems, other computers, custom software and additional experimental hardware.


REAL-TIME BCI CONTROL IN PRACTICE
g.HIsys has been used to control an excavator from P300 brain signals. EEG data were calibrated in g.BSanalyze and processed in real time with g.HIsys to determine the user’s intended command.
CLOSED-LOOP MOTOR IMAGERY WITH FES
Build real-time motor imagery BCIs directly in Simulink. g.HIsys can acquire EEG, apply CSP-based spatial filtering and bandpass processing, extract signal features, classify left- and right-hand motor imagery and use the classification result to trigger functional electrical stimulation.
The complete pipeline from EEG acquisition and signal processing to classification and stimulation is implemented in the same real-time environment.


REAL-TIME EEG + fNIRS INTEGRATION
g.HIsys enables synchronized acquisition, visualization and real-time processing of EEG and fNIRS data within Simulink. EEG can be acquired with g.HIamp, g.USBamp or g.Nautilus while fNIRS data are processed simultaneously, enabling multimodal studies of electrophysiological and hemodynamic activity.
NIRx NIRsport2 and Artinis Brite/Brite Lite systems can be integrated through Lab Streaming Layer.
BUILD YOUR OWN REAL-TIME BIOSIGNAL APPLICATIONS
g.HIsys provides a modular Simulink block library covering the complete real-time processing chain: acquisition, preprocessing, signal transformation, feature extraction, classification, visualization, stimulation and data storage.
Available blocks include source derivation, bandpass and notch filtering, triggering, channel selection, FFT, ERD, PSD, spectrograms, statistical analysis, EMG/EOG control, UDP and Lab Streaming Layer. Researchers can combine these blocks with standard Simulink functionality or extend them with their own MATLAB and C algorithms.
REAL-TIME CONTROL OF STIMULATION
g.HIsys can control g.Estim PRO and g.Estim FES directly from Simulink. Stimulation parameters and triggers can be controlled in real time, enabling closed-loop experiments that link biosignal activity to electrical stimulation.
For g.Estim PRO, stimulation can be routed through the 256-channel switching unit. g.Estim FES provides real-time control of phase duration and amplitude together with stimulation-status and safety-related feedback.
NEUROMODULATION, CCEP AND CORTICAL MAPPING
g.HIsys supports real-time data acquisition and stimulation workflows for neuromodulation research, including CCEP screening, electrical cortical stimulation mapping and somatosensory evoked potential mapping. The system can coordinate acquisition, stimulation and channel switching within the same experimental environment.
DESIGN AND RUN MULTIMODAL EXPERIMENTS
The Paradigm Presenter lets researchers create synchronized experimental paradigms using video, audio, text, images and digital I/O. Experimental events and task timing can be stored together with the biosignal data for subsequent analysis in g.BSanalyze.
REAL-TIME FEATURE EXTRACTION AND CLASSIFICATION
Extract and analyze biosignal features directly during an experiment. g.HIsys provides blocks for power spectrum, FFT, ERD, pre/post-stimulus PSD, spectrograms, averages and significance analysis. These features can be used as inputs for real-time classification and BCI control.
Standard Simulink blocks can be combined with custom MATLAB or C algorithms to create application-specific processing and classification pipelines.
DISTRIBUTED EEG ACQUISITION
Distributed EEG allows g.tec amplifiers connected to different PCs to send synchronized biosignal data to a central evaluation and storage computer. Data synchronization uses OSC, while UDP handles network transmission.
OSCAR LIVE: REAL-TIME EEG ARTIFACT REMOVAL
OSCAR LIVE removes common EEG artifacts in real time while preserving the neural signal needed for BCI and neuroscience applications. It is designed for continuous EEG acquisition where eye movements, muscle activity and other physiological artifacts can otherwise affect real-time analysis and classification.
Integrated directly into g.HIsys, OSCAR LIVE can be used as part of a real-time processing pipeline before feature extraction, classification, visualization or closed-loop control. This enables researchers to work with cleaner EEG signals during the experiment rather than relying exclusively on offline artifact correction.
REAL-TIME SIGNAL QUALITY AND BIOSIGNAL CONTROL
Monitor signal quality while the experiment is running and use physiological signals as real-time control inputs. EEG Quality Check and EEG Quality Display support real-time artifact detection, while impedance and other signal-quality parameters can be visualized during acquisition.
g.HIsys also provides dedicated EMG and EOG processing for muscle- and eye-movement control, including RMS-based EMG thresholds, calibration routines, eye-blink and eye-movement selection, spasticity monitoring and 2D EMG control.
SIMULATE, AUTOMATE AND TRANSFORM SIGNALS
Develop and test real-time applications without an amplifier using the Real Time Clock, which simulates real-time model execution. Once an experiment is complete, Automatic Batch Starter can automatically launch predefined offline processing steps.
g.HIsys also provides dedicated blocks for channel selection, epoch extraction, event selection, trigger generation and binary decoding, allowing researchers to build reproducible signal-processing workflows for evoked potentials, BCI experiments and other time-locked paradigms.
MULTI-AMPLIFIER AND MULTI-USER ACQUISITION
g.HIsys can acquire simultaneously from multiple g.tec amplifiers, including mixed amplifier types and different sampling frequencies. Multiple amplifiers can be combined in one Simulink model, enabling recordings beyond 256 channels and simultaneous acquisition from multiple subjects on one computer.
REAL-TIME 3D BRAIN MAPPING
Visualize biosignal activity directly on 3D head and cortical models during acquisition. g.HIsys provides Bubble Scope for electrode-level activation mapping, Interpolation Scope and Multi Interpolation Scope for projecting activity onto the head or cortex, and Selection Scope 3D for selecting and categorizing electrodes directly on the model.
The Data Quality Scope can also map signal-quality parameters such as impedance onto the skull or cortical surface, combining functional activity and recording quality in a single 3D environment.
REAL-TIME STIMULATION CONTROL
g.HIsys enables synchronized, real-time control of g.tec stimulation hardware directly from biosignal-processing workflows. Control auditory stimulation, vibro-tactile stimulation and functional electrical stimulation while generating precisely aligned triggers for EEG analysis.
The platform supports auditory stimulation of the left and right ear, vibro-tactile stimulation at up to seven body locations, and bipolar, biphasic FES through two stimulation channels for applications involving the hand, leg and other target locations.
REAL-TIME PHYSIOLOGICAL STATE CLASSIFICATION
Physio Observer combines multimodal biosignal acquisition, real-time feature extraction and classification to estimate a subject’s physiological or cognitive state during an experiment.
Acquire ECG, EEG, EMG, GSR, respiration, temperature, acceleration and oxygen saturation using g.USBamp, g.HIamp or g.Nautilus. Experimental paradigms can be synchronized with these signals to study defined states such as workload, emotion or memory performance.
Physiological parameters such as heart rate, heart-rate variability, respiration and GSR can be extracted and classified in real time. Classification results and calculated parameters can then be transmitted to external applications via UDP for real-time feedback and closed-loop control.
BUILD YOUR OWN REAL-TIME NEUROTECHNOLOGY APPLICATIONS
Use standard Simulink blocks, MATLAB S-Functions or C S-Functions to develop your own real-time processing algorithms and applications. Connect g.tec amplifiers, external data streams and experimental hardware within the same workflow, then use LSL or UDP to exchange signals and control information with external applications.


FROM EXPERIMENT CONCEPT TO READY-TO-RUN APPLICATION
Developing a real-time neuroscience application does not have to start from scratch. g.tec can provide preconfigured experiment setups and develop the required g.HIsys building blocks for a specific research workflow.
Depending on the application, the setup can include biosignal acquisition, real-time processing, feature extraction, classification, visualization, event handling, and interfaces to stimulation or external devices. This enables researchers to start with a functional application and adapt it to their experimental requirements rather than developing the complete system themselves.
g.tec supports the implementation of BCI, closed-loop stimulation, multimodal acquisition and other real-time neuroscience applications, from initial experiment design through to a ready-to-deploy setup.
PART OF THE G.TEC SOFTWARE ECOSYSTEM
g.HIsys is part of the g.tec Suite 2024, which combines g.NEEDaccess, g.HIsys, g.BSanalyze and g.Recorder in one software environment. The Suite simplifies installation, updates and software compatibility across the g.tec ecosystem.
Researchers can combine real-time acquisition and processing in g.HIsys with offline analysis in g.BSanalyze and recording workflows in g.Recorder, while g.NEEDaccess provides access to the underlying APIs and interfaces.
g.HISYS BASIC
For real-time acquisition and signal visualization. Real-time acquisition from g.USBamp, g.HIamp, g.Nautilus and Unicorn BCI Core-8, with full amplifier control and ultra-fast visualization of up to 1,024 channels.
Includes:
1 block library · 5 Simulink models · amplifier control · raw data visualization · onboarding
g.HISYS PROFESSIONAL
For BCI development, real-time processing and closed-loop experiments. The complete g.HIsys development environment for advanced neuroscience research, with real-time signal processing, BCI development, multimodal acquisition, stimulation and closed-loop applications.
Includes:
19 block libraries · 118 Simulink models · 89 signal-processing blocks · OSCAR LIVE · Paradigm Presenter · BCI applications · TMS · ECoG · fNIRS · eye tracking · LSL · 3D visualization · neuromodulation · VR/AR · hyperscanning
CLOSED-LOOP EEG, FES AND TMS EXPERIMENTS
See how g.tec technology can combine real-time EEG processing with FES and TMS in closed-loop experiments. The presentation demonstrates how brain activity can be acquired, analyzed and used to control stimulation in real time.
REAL-TIME CORTICAL ACTIVITY MAPPING
The Bubble Scope 3D visualizes significant brain activity directly on reconstructed patient anatomy, including implanted ECoG grids. This enables researchers to identify and monitor spatial patterns of cortical activation in real time.
CENTRAL SULCUS MAPPING WITH ECoG
g.HIsys can visualize evoked potentials from ECoG recordings to identify the functional boundary between sensory and motor cortex. In the demonstrated vibro-tactile paradigm, phase reversal between cortical areas reveals the central sulcus, while high-quality acquisition enables the result with only a small number of stimuli.
REAL-TIME EPILEPSY MONITORING
g.HIsys enables simultaneous visualization and analysis of implanted ECoG signals during epilepsy research. Raw and high-gamma-filtered signals can be monitored while the Bubble Scope 3D maps changes in cortical activity, allowing seizure propagation to be visualized across recording sites in real time.
ULTRA-HIGH-DENSITY BRAIN MAPPING
g.HIsys Professional supports real-time visualization of cortical activity recorded with the g.Pangolin ultra-high-density EEG system. Electrode locations can be defined interactively using the g.Pangolin Montage Creator, enabling spatial visualization of high-density EEG recordings.
MULTIMODAL NEUROIMAGING: MEG, EEG AND ECoG
Explore multimodal approaches combining MEG, EEG and ECoG for advanced epilepsy research and cortical investigation.
OSCAR FOR EEG AND ECoG ARTIFACT REMOVAL
OSCAR removes artifacts from EEG and ECoG recordings acquired with g.tec biosignal amplifiers, helping researchers recover cleaner neural signals from recordings affected by movement, muscle activity and other interference.
OSCAR LIVE FOR REAL-TIME ARTIFACT REMOVAL
OSCAR LIVE removes EEG artifacts during acquisition while preserving the underlying evoked response. In visual evoked-potential experiments, real-time artifact removal improves signal quality without requiring offline preprocessing, enabling cleaner signals for immediate analysis and closed-loop applications.
g.HIsys Professional combines OSCAR LIVE with real-time acquisition, processing and visualization, while data can be stored in MATLAB format for subsequent analysis in g.BSanalyze.
OSCAR LIVE FOR AUDITORY EVOKED POTENTIALS
See how OSCAR LIVE removes movement, muscle and eye-related artifacts during auditory evoked-potential recordings while preserving the underlying neural response. The result is improved AEP visibility directly during real-time acquisition.
REAL-TIME EVOKED POTENTIAL ANALYSIS
The Evoked Potential Scope displays multiple averaged traces per channel, including target and non-target responses in oddball paradigms. Statistical analysis identifies significant differences directly within the scope, supporting rapid evaluation of evoked responses during experiments.
SYNCHRONIZED EXPERIMENT DATA
The Paradigm Presenter can save task names, timing information and experimental events together with EEG data. This keeps experimental timing synchronized with the recorded biosignals and provides the information required for subsequent analysis in g.BSanalyze.
FREQUENTLY ASKED QUESTIONS
g.HIsys Professional is designed for real-time neuroscience applications ranging from BCI development to multimodal and closed-loop experiments. Researchers can build P300, SSVEP, motor imagery and hybrid BCI applications; develop real-time signal-processing and classification pipelines; integrate EEG with ECoG, EMG, EOG, ECG, fNIRS and other biosignals; and control stimulation or external devices based on real-time biosignal activity. Professional also provides tools for TMS, ECoG, CCEP, distributed EEG, 3D visualization, eye tracking, VR/AR and hyperscanning.
Yes. g.HIsys is a rapid-prototyping environment built around MATLAB and Simulink. Researchers can combine standard Simulink blocks with g.HIsys acquisition and processing blocks and implement their own algorithms using MATLAB S-Functions or C S-Functions. The resulting models can run in real time without compiling the Simulink model.
g.HIsys supports real-time acquisition and processing of EEG, ECoG, ECG, EMG, EOG and fNIRS, with additional support for spike data and wireless acquisition through g.Nautilus. The acquisition blocks connect the biosignal amplifier directly to the Simulink processing model, allowing the incoming signals to be filtered, transformed, analyzed, visualized and stored during the experiment.
Yes. Real-time biosignal processing can be connected to g.tec stimulation interfaces to create closed-loop experiments. Depending on the Professional configuration, this includes interfaces for g.Estim PRO, g.Estim FES, g.STIMbox and other stimulation hardware, as well as TMS-related workflows. This allows detected brain or physiological activity to trigger or control stimulation within the experimental loop.
g.HIsys provides dedicated blocks for preprocessing, transformation, feature extraction, analysis, classification, visualization and data storage. For example, the FFT block can calculate FFT, power spectrum or power spectral density with configurable windows, averaging and overlap, while averaging blocks can calculate running or moving-window averages for incoming trials.
Yes. g.HIsys Professional includes ready-to-run BCI applications and processing workflows for P300, SSVEP and motor imagery. For P300 experiments, for example, the system supports classifier generation using Linear Discriminant Analysis or Support Vector Machines, with g.BSanalyze used to calculate classifiers from acquired EEG datasets for subsequent feedback experiments.
Yes. g.HIsys Professional provides interfaces for technologies such as LSL and UDP, as well as remote and distributed acquisition workflows. This allows real-time signal or trigger information to be exchanged with external applications and experimental systems rather than keeping the processing pipeline isolated inside Simulink. The user manual also documents both Simulink- and MATLAB-based UDP interfaces.
Yes. The Paradigm functionality supports synchronized experimental paradigms and can work with stimuli such as audio, video, pictures and text, as well as digital outputs and external messaging. Experimental events can be incorporated into the real-time workflow so that stimulus timing and biosignal data remain aligned for subsequent analysis.
Yes. g.HIsys Professional includes ECoG and cortico-cortical evoked potential workflows and provides real-time 3D visualization capabilities. The Bubble Scope can visualize significant ECoG activity on reconstructed brain anatomy, while ECoG-based evoked potentials can be used for applications such as central sulcus mapping. The platform has also been used to visualize seizure propagation across implanted ECoG recording sites in real time.
g.HIsys BASIC provides the core real-time acquisition environment, including amplifier blocks for g.USBamp, g.HIamp and g.Nautilus and raw-data visualization of up to 1,024 channels. PROFESSIONAL adds the advanced research toolboxes and interfaces required for BCI development, stimulation, multimodal acquisition, ECoG, fNIRS, TMS, eye tracking, distributed EEG, 3D visualization and other advanced applications.




